Moi Exposito-Alonso

Moi Exposito-Alonso Portrait

Howard Hughes Medical Institute Freeman Hrabowski Scholar and Assistant Professor

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Research Description

Moisés Expósito Alonso investigates the genetic processes driving species adaptation or extinction in response to new environments caused by climate change. Centered on model plant species, Expósito Alonso’s team integrates long-term evolutionary experiments in field sites worldwide with molecular biology and genomics to explore the gene pathways underlying plant climate adaptation, and the speed and predictability of rapid evolution. By employing biodiversity modeling informed by genomics, this research is unveiling the impact of climate and land transformations on species evolution and the loss of genetic diversity globally.

Selected Publications

Understanding local plant extinctions before it’s too late: bridging evolutionary genomics with global ecology.
Exposito-Alonso, M. New Phytologist (2022), (Tansley Medal)

Genetic diversity loss in the Anthropocene.
Exposito-Alonso, M., Booker, T. A., Czech, L., Gillespie, L., Hateley, S., Kyriazis, C. C., Lang, P. Leventhal, L. Nogues-Bravo, D., Pagowski, V. Ruffley, M., Spence, J. P., Toro Arana, S., Weiss, C. and Zess, Erin. Science

A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation.
Dorone, Y., Boeynaems, S., Flores, E.; Jin, B. Hateley, S., Bossi, F., Elena L., Pennington J.G.; Michiels, E., De Decker, M., Vints, K., Baatsen, P., Bassel, G.W.,  Otegui, M.S., Holehouse, A.S., Exposito-Alonso, M., Sukenik, S., Gitler, A.D., Rhee, S.Y. Cell (2021)

Mutation bias reflects natural selection in Arabidopsis thaliana.
Monroe, J Grey; Srikant, Thanvi; Carbonell-Bejerano, Pablo; Becker, Claude; Lensink, Mariele; Exposito-Alonso, Moises; Klein, Marie; Hildebrandt, Julia; Neumann, Manuela; Kliebenstein, Daniel; Weng, Mao-Lun; Imbert, Eric; Ågren, Jon; Rutter, Matthew T; Fenster, Charles B; Weigel, Detlef. 2022 Nature.

Seasonal timing adaptation across the geographic range of Arabidopsis thaliana.
Exposito-Alonso M. (2020). PNAS, 117 (18) 9665-9667

Genomic Prediction of (Mal)Adaptation across Current and Future Climatic Landscapes.
Capblancq T, Fitzpatrick MC, Bay RA, Exposito-Alonso M, and Keller S R. Annual Reviews of Ecology, Evolution, and Systematics (2020) 51 (1): 245–69.

Natural selection on the Arabidopsis thaliana genome in present and future climates.
Exposito-Alonso, M., 500 Genomes Field Experiment Team, Burbano, H. A., Bossdorf, O., Nielsen, R., Weigel, D. Nature (2019),

Genomic basis and evolutionary potential for extreme drought adaptation in Arabidopsis thaliana.
Exposito-Alonso, M., Vasseur, F., Ding, W., Wang, G., Burbano, H.A., Weigel, D., (2018). Nature Ecology & Evolution 2, 352–358.

Adaptive diversification of growth allometry in the plant Arabidopsis thaliana.
Vasseur, F., Exposito-Alonso, M., Ayala-Garay, O., Wang, G., Enquist, B.J., Violle, C., Ville, D., Weigel, D., (2018) PNAS,

The rate and effect of new mutations in a colonizing plant lineage.
Exposito-Alonso, M.*, Becker, C*., Schuenemann, V.J., Reitter, E., Setzer, C., Slovak, R., Brachi, B., Hagmann, J., Grimm, D.G., Jiahui, C., Busch, W., Bergelson, J., Ness, R.W., Krause, J., Burbano, H.A., Weigel, D., (2018) PLOS Genetics, 14, e1007155.

1,135 Genomes reveal the global pattern of polymorphism in Arabidopsis thaliana.
1001 Genomes Consortium Cell (2016) 166, 481–491.