Recent Publications

PubMed Listing for Michael Nachman


Suzuki, T. A., and M. W. Nachman. (2016). Spatial Heterogeneity of Gut Microbial Composition along the Gastrointestinal Tract in Natural Populations of House Mice. PloS one 11.9, e0163720.

Weyand, N. J., Ma, M., Phifer-Rixey, M., Taku, N. A., Rendón, M. A., Hockenberry, A. M., et al. (2016). Isolation and characterization of Neisseria musculi sp. nov., from the wild house mouse. International journal of systematic and evolutionary microbiology, 66(9), 3585-3593.

Sheehan, M. J., Lee, V., Corbett-Detig, R., Bi, K., Beynon, R. J., Hurst, J. L., and Nachman, M. W. 2016. Selection on Coding and Regulatory Variation Maintains Individuality in Major Urinary Protein Scent Marks in Wild Mice. PLoS Genet, 12(3):e1005891.

Mack, K. L., Campbell, P., and Nachman, M. W. 2016. Gene regulation and speciation in house mice. Genome research, 26:451–461.

Holmes, M.W., Hammond, T.T., Wogan, G.O., Walsh, R.E., LaBarbera, K., Wommack, E.A., Martins, F.M., Crawford, J.C., Mack, K.L., Bloch, L.M. and Nachman, M.W. 2016. Natural history collections as windows on evolutionary processes. Molecular ecology, 25(4):864–881.


Suzuki, T.A. and M.W. Nachman. 2015. Speciation and hybrid female fertility in house mice. Evolution, 69(9):2468-2481.

Phifer-Rixey, M. and M. W. Nachman. 2015. The natural history of model organisms: Insights into mammalian biology from the wild house mouse Mus musculus. eLife, 4:e05959.


Sheehan, M. J. and Nachman, M. W. 2014. Morphological and population genomic evidence that human faces have evolved to signal individual identity. Nature communications, 5:4800.

Carneiro, M., Albert, F. W., Afonso, S., Pereira, R. J., Burbano, H., Campos, R., et al. 2014. The genomic architecture of population divergence between subspecies of the European rabbit. PLoS genetics, 10(8), e1003519.

Phifer-Rixey, M., Bomhoff, M., & Nachman, M. W., 2014. Genome-Wide Patterns of Differentiation Among House Mouse Subspecies. Genetics, 198(1), 283-297.

Lüke, L., P. Campbell, M.V. Sánchez, M.W. Nachman, and E.R.S. Roldan, 2014. Sexual selection on protamine and transition nuclear protein expression in mouse species. Proc. R. Soc. B 281:20133359; doi:10.1098/rspb.2013.3359

Rocha, L. A., Aleixo, A., Allen, G., Almeda, F., Baldwin, C. C., Barclay, M. V. L., et al., 2014. Specimen collection: An essential tool. Science, 344:814-815.

Seehausen, O., Butlin K.J., Keller I., Wagner C.E., Boughman J.E., Hohenlohe P.A., Peichel C.L., Saetre G. et al, 2014. Genomics and the origin of species. Nature Reviews Genetics, 15:176-192.

Campbell, P., M.W. Nachman. 2014. X-Y Interactions Underlie Sperm Head Abnormality in Hybrid Male House Mice. Genetics, 196(4):1231-1240.


Nachman, M.W. Genomics and museum specimens. 2013. Molecular ecology: 22(24):5966-8.

Carneiro, M., S.J.E. Baird, S. Afonso, E. Ramirez, P. Tarroso, H. Teotonio, R. Villafuerte, M.W. Nachman, and N. Ferrand. 2013. Steep clines within a highly permeable genome across a hybrid zone between two subspecies of the European rabbit. Molecular Ecology, 22: 2511-2525.

Campbell, P., J.M. Good, and M.W. Nachman, 2013. Meiotic sex chromosome inactivation is disrupted in sterile hybrid male house mice. Genetics, 193:819-828.


Campbell, P., J.M. Good, M.D. Dean, P.K. Tucker, and M.W. Nachman. 2012. The contribution of the Y chromosome to hybrid male sterility in house mice. Genetics, 191(4):1271-1281.

Phifer-Rixey, M., F. Bonhomme, P. Boursot, G.A. Churchill, J. Pialek, P.K. Tucker, and M.W. Nachman. 2012. Adaptative evoluton and effective population size in wild house mice. Molecular Biology and Evolution 29(10): 2949-2955.

Janousek, V., L. Wang, K. Luzynski, P. Dufkova, M.M. Vyskocilova, M.W. Nachman, P. Munclinger, M. Macholan, J. Pialek, and P.K. Tucker. 2012. Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus and M. m. domesticus. Molecular Ecology 21(12):3032-3047.

Carnerio, M., F.W. Albert, J. Melo-Ferreira, N. Galtier, P. Gayral, J.A. Blanco-Aguiar, R. Villafuerte, M.W. Nachman, N. Ferrand, 2012. Evidence for widespread positive and purifying selection across the European rabbit (Oryctolagus cuniculus) genome. Molecular Biology and Evolution, 29(7):1837-1849.

Nachman, M.W. and B.A. Payseur. 2012. Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice. Philosophical Transactions of the Royal Society B, 367: 409-421.


Geraldes, A., P. Basset, K.L. Smith, and M.W. Nachman, 2011. Higher differentiation among subspecies of the house mouse (Mus musculus) in genomic regions with low recombination. Molecular Ecology 20(22): 4722-4736.

Song, Y., S. Endepols, N. Klemann, D. Richter, F.-R. Matuschka, C.-H. Shih, M.W. Nachman, and M.H. Kohn, 2011. Adaptive introgression of anticoagulant rodent poison resistance by hybridization between Old World mice. Current Biology 21: 1296-1301.

Dean, M.D., G.D. Findlay, M.R. Hoopmann, C.C. Wu, M.J. MacCoss, W.J. Swanson, and M.W. Nachman, 2011. Identification of ejaculated proteins in the house mouse (Mus domesticus) via isotopic labeling. BMC Genomics 12: 306.

Yang, H., J.R. Wang, J.P. Didion, R.J. Buus, T.A. Bell, C.E. Welsh, F. Bonhomme, H.T. Yu, M.W. Nachman, J. Pialek, P.K. Tucker, P. Boursot, L. McMillan, G.A. Churchill, and F. Pardo-Manuel de Villena, 2011.  Subspecific origin and haplotype diversity in the laboratory mouse.  Nature Genetics 43: 648-655.

Wang, L., K. Luzynski, J. Pool, V. Janoušek, P. Dufková, M. Vyskocilová, K.C. Teeter, M.W. Nachman, P. Munclinger, M. Macholán, J. Piálek, and P.K. Tucker, 2011. Measures of linkage disequilibrium among neighboring SNPs indicate asymmetries across the house mouse hybrid zone. Molecular Ecology 20:2985-3000.

Reifova, R., J. Reif, M. Antczak, and M.W. Nachman, 2011. Ecological character displacement in the face of gene flow: evidence from two species of nightingales.  BMC Evolutionary Biology 11: 138.

Carneiro, M., S. Afonso, A. Geraldes, H. Garreau, G. Bolet, S. Boucher, A. Tircazes, G. Queney, M.W. Nachman, and N. Ferrand, 2011. The genetic structure of domestic rabbits. Molecular Biology and Evolution, 28(6): 1801-1816.

Good, J.M., D. Vanderpool, K.L. Smith, and M.W. Nachman, 2011. Extraordinary sequence divergence at Tsga8, an X-linked gene involved in mouse spermiogensis. Molecular Biology and Evolution, 28(5): 1675-1686.


Good, J.M., T. Giger, M.D. Dean, and M.W. Nachman, 2010. Widespread over-expression of the X chromosome in sterile F1 hybrid mice. PLoS Genetics 6(9): e1001148.

Carneiro, M., J.A. Blanco-Aguiar, R. Villafuerte, N. Ferrand, M.W. Nachman, 2010. Speciation in the European rabbit (Oryctolagus cuniculus): Islands of differentiation on the X-chromosome and autosomes. Evolution, 64(12): 3443-3460.

Geraldes, A., T. Rambo, R. Wing, N. Ferrand, and M.W. Nachman, 2010. Extensive gene conversion drives the concerted evolution of paralogous copies of the SRY gene in European rabbits. Molecular Biology and Evolution, 27(11): 2437-2440.

Wlasiuk, G., and M.W. Nachman, 2010. Adaptation and contraint at toll-like receptors in primates. Molecular Biology and Evolution, 27(9): 2172-2186.

Wlasiuk, G., and M.W. Nachman, 2010. Promiscuity and the rate of molecular evolution at primate immunity genes. Evolution 64(8): 2204-2220.

Teeter, K.C., L.M. Thibodeau, Z. Gompert, C.A. Buerkle, M.W. Nachman, and P.K. Tucker, 2010. The variable genomic architecture of isolation between hybridizing species of house mice. Evolution, 64(2): 472-485.

Storchova, R., J. Reif, and M.W. Nachman, 2010. Female heterogamety and speciation: Reduced introgression of the Z chromosome between two species of nightingales. Evolution, 64(2): 456-471.


Dean, M.D., N.L. Clark, G.D. Findlay, R.C. Karn, X. Yi, W.J. Swanson, M.J. MacCoss, and M.W. Nachman, 2009. Proteomics and comparative genomic investigations reveal heterogeneity in evolutionary rate of male reproductive proteins in mice (Mus domesticus). Molecular Biology and Evolution, 26(8): 1733-1743.

Wlasiuk, G., S. Khan, W.M. Switzer, and M.W. Nachman, 2009. A history of recurrent positive selection at the Toll-like receptor 5 in primates. Molecular Biology and Evolution, 26(4): 937-949.

Carneiro, M., N. Ferrand, and M.W. Nachman, 2009. Recombination and speciation: Loci near centromeres are more differentiated than loci near telomeres between subspecies of the European rabbit (Oryctolagus cuniculus). Genetics, 181: 593-606.

Dean, M.D., and M.W. Nachman, 2009. Faster fertilization rate in conspecific versus heterospecific matings in house mice. Evolution 63: 20-28.


Geraldes, A., M. Carneiro, M. Delibes-Mateos, R. Villafuerte, M.W. Nachman, and N. Ferrand, 2008. Reduced introgression of the Y chromosome between subspecies of the European rabbit (Oryctolagus cuniculus) in the Iberian Peninsula. Molecular Ecology, 17: 4489-4499.

Geraldes, A., P. Basset, B. Gibson, K. Smith, B. Harr, H.T. Yu, N. Bulatova, Y. Ziv, and M.W. Nachman, 2008. Inferring the history of speciation in house mice from autosomal, X-linked, Y-linked and mitochondrial genes. Molecular Ecology, 17: 5349-5363.

Good, J.M., M.D. Dean, and M.W. Nachman, 2008. A complex genetic basis to X-linked hybrid male sterility between two species of house mice. Genetics 179: 2213-2228.

Good, J.M., M.A. Handel, and M.W. Nachman, 2008. Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house mice. Evolution 62(1): 50-65.

Dean, M.D., J.M. Good, and M.W. Nachman, 2008.  Adaptive evolution of proteins secreted during sperm maturation: an analysis of the mouse epididymal transcriptome.  Molecular Biology and Evolution, 25(2): 383-392. 

Teeter, K.C., B.A. Payseur, L.W. Harris, M.A. Bakewell, L.M. Thibodeau, J.E. O´Brien, J.G. Krenz, M.A. Sans-Fuentes, M.W. Nachman, and P.K. Tucker, 2008. Genome-wide patterns of gene flow across a house mouse hybrid zone. Genome Research 18: 67-76.


Salcedo, T., A. Geraldes, and M.W. Nachman, 2007. Nucleotide variation in wild and inbred mice. Genetics 177: 2277-2291.

Wlasiuk, G. and M.W. Nachman, 2007. The genetics of adaptive coat color in gophers: Coding variation at Mc1r is not responsible for dorsal color differences. Journal of Heredity 98(6): 567-574.

Laurie, C.C, D.A. Nickerson, A.D. Anderson, B.S. Weir, R.J. Livingston, M.D. Dean, K.L. Smith, E.E. Schadt, and M.W. Nachman, 2007. Linkage disequilibrium in wild mice. PLoS Genetics, 3(8): e144.

Storz, J.F., S.J. Sabatino, F.G. Hoffmann, E.J. Gering, H. Moriyama, N. Ferrand, B. Monteiro, and M.W. Nachman, 2007. The molecular basis of high-altitude adaptation in deer mice. PLoS Genetics 3(3): 0448-0459.


Saunders, M.A., J.M. Good, E.C. Lawrence, R.E. Ferrell, W-H. Li, and M.W. Nachman, 2006. Human Adaptive Evolution at Myostatin (GDF8), a Regulator of Muscle Growth. American Journal of Human Genetics, 79: 1089-1097.

Dean, M.D., K.G. Ardlie, and M.W. Nachman, 2006. The frequency of multiple paternity suggests that sperm competition is common in house mice Mus domesticus. Molecular Ecology 15: 4141-4151.

Geraldes, A., N. Ferrand, and M.W. Nachman, 2006. Contrasting patterns of introgression at X-linked loci across the hybrid zone between subspecies of the European rabbit (Oryctolagus cuniculus). Genetics 173: 919-933.

Nachman, M.W., 2006. Detecting selection at the molecular level. In: Evolutionary Genetics, Concepts and Case Studies, edited by C.W. Fox and J.B. Wolf. Oxford University Press, Oxford.


Wood, E.T., D.A. Stover, M. Slatkin, M.W. Nachman, and M.F. Hammer, 2005. The beta-globin recombinational hotspot reduces the effects of genetic hitchhiking around HbC, a recently arisen mutation providing resistance to malaria. American Journal of Human Genetics, 77: 637-642.

Saunders, M.A., M. Slatkin, C. Garner, M.F. Hammer, and M.W. Nachman, 2005. The extent of linkage disequilibrium caused by selection on G6PD in humans. Genetics 171: 1219-1229.

Hoekstra, H.E., and M.W. Nachman, 2005. Coat color variation in rock pocket mice (Chaetodipus intermedius): from genotype to phenotype, pp. 79-99 in Mammalian Diversification: From Chromosomes to Phylogeography, E. Lacey and P. Myers, Eds. University of California Publications in Zoology.

Good, J. M. and Nachman, M. W. 2005. Rates of protein evolution are positively correlated with timing of expression during mouse spermatogenesis. Molecular Biology and Evolution 22:1044-1052.

Payseur, B.A., and M.W. Nachman, 2005. The genomics of speciation: investigating the molecular correlates of X chromosome introgression across the hybrid zone between Mus domesticus and Mus musculus. Biol. J. Linn. Soc 84: 523-534.

Nachman, M.W. 2005. The genetic basis of adaptation: lessons from concealing coloration in pocket mice. Genetica 123:125-136.

Hoekstra, H.E., J.G. Krenz, and M.W. Nachman, 2005. Local adaptation in the rock pocket mouse (Chaetodipus intermedius): natural selection and phylogenetic history of populations. Heredity 94: 217-228.

Nachman, M.W., 2004. Haldane and the first estimates of the human mutation rate. J. Genet. 83: 231-233.

Payseur, B.A., J.G. Krenz, and M.W. Nachman, 2004. Differential patterns of introgression across the X chromosome in a hybrid zone between two species of house mice. Evolution 58: 2064-2078. (Erratum)

Hammer, M.F., D. Garrigan, E. Wood, J.A. Wilder, Z. Mobasher, A. Bigham, J.G. Krenz, and M.W. Nachman, 2004. Heterogeneous patterns of variation among multiple X linked loci: the possible role of diversity reducing selection in non-Africans. Genetics 167: 1841-1853.

Rosenblum, E.B., H.E. Hoekstra, and M.W. Nachman, 2004. Adaptive reptile color variation and the evolution of the Mc1r gene. Evolution 58: 1794-1808.

Storz, J.F., B.A. Payseur, and M.W. Nachman, 2004. Genome scans of microsatellite variability in humans reveal evidence for selective sweeps outside of Africa. Mol. Biol. Evol. 21: 1800-1811.

Hoekstra, H.E., K.E. Drumm, and M.W. Nachman, 2004. Ecological genetics of adaptive color polymorphism in pocket mice: geographic variation in selected and neutral genes. Evolution 58: 1329-1341.

Nachman, M.W., S.L. D'Agostino, C.R. Tillquist, Z. Mobasher, and M.F. Hammer, 2004. Nucleotide variation at Msn and Alas2, two genes flanking the centromere of the X chromosome in humans. Genetics 167: 423-437.

Storz, J.F. and M.W. Nachman, 2003. Natural selection on protein polymorphism in the rodent genus Peromyscus: evidence from interlocus contrasts. Evolution 57: 2628-2635.

Hammer, M.F., F. Blackmer, D. Garrigan, M.W. Nachman, and J.A. Wilder. 2003. Human population structure and its effects on sampling Y chromosme sequence variation. Genetics 164: 1495-1509.

Nachman, M.W., Hoekstra, H.E., and S.L. D'Agostino, 2003. The genetic basis of adaptive melanism in pocket mice. Proc. Nat. Acad. Sci. USA 100: 5268-5273.

Hoekstra, H.E., and M.W. Nachman, 2003. Different genes underlie adaptive melanism in different populations of rock pocket mice. Mol. Ecol. 12: 1185-1194.

Saunders, M.A., M.F. Hammer, and M.W. Nachman, 2002. Nucleotide variability at G6pd and the signature of malarial selection in humans. Genetics 162:1849-1861.

Nachman, M.W. 2002 Variation in recombination rate across the genome: evidence and implications. Curr. Op. Genet. Devel. 12: 657-663.

Payseur, B.A., and M.W. Nachman, 2002. Natural selection at linked sites in humans. Gene 300: 31-42.

Payseur, B.A., A.D. Cutter, and M.W. Nachman, 2002. Searching for evidence of positive selection in the human genome using patterns of microsatellite variability. Mol. Bio. Evol. 19: 1143-1153.

Payseur, B.A., and M.W. Nachman, 2002. Gene density and human nucleotide polymorphism. Mol. Biol. Evol. 19: 336-340.

Nachman, M.W. 2001. Single nucleotide polymorphisms and recombination rate in humans. Trends in Genetics 17: 481-485.

Riginos, C., and M.W. Nachman, 2001. Population subdivision in marine environments: the contributions of isolation by distance, discontinuous habitat, and biogeography to genetic differentiation in a blennioid fish, Axoclinus nigricaudus. Molecular Ecology 10: 1439-1453.

Payseur, B.A., and M.W. Nachman, 2000. Microsatellite variation and recombination rate in the human genome. Genetics 156: 1285-1298.

Gilad, Y., D. Segre, K. Skorecki, M.W. Nachman, D. Lancet, and D. Sharon, 2000. Dichotomy of single-nucleotide polymorphism haplotypes in olfactory receptor genes and pseudogenes. Nature Genetics 26: 221-224.

Nachman, M.W., and S.L. Crowell, 2000. Estimate of the mutation rate per nucleotide in humans. Genetics 156: 297-304. Romanian translation

Nachman, M.W., and S.L. Crowell, 2000. Contrasting evolutionary histories of two introns of the Duchenne muscular dystrophy locus, Dmd, in humans. Genetics 155: 1855-1864.

Riginos, C., and M.W. Nachman, 1999. The origin of a Robertsonian chromosomal translocation in house mice inferred from linked microsatellite markers. Molecular Biology and Evolution 16: 1763-1773.

Karn, R. C., and M.W. Nachman, 1999. Reduced nucleotide variability at the salivary androgen-binding locus in house-mice; evidence for positive natural selection. Molecular Biology and Evolution 16: 1192-1197.

Nachman, M.W., 1998. Y-chromosome variation of mice and men. Molecular Biology and Evolution 15: 1744-1750.

Nachman, M.W., V.L. Bauer, S.L. Crowell, and C.F. Aquadro, 1998. DNA variability and recombination rates at X-linked loci in humans. Genetics 150: 1133-1141.

Kennedy, P., and M.W. Nachman, 1998. Deleterious mutations at the mitochondrial ND3 gene in South American marsh rats (Holochilus). Genetics 150: 359-368.

Nachman, M.W., 1998. Deleterious mutations in animal mitochondrial DNA. Genetica 102/103: 61-69.

Nachman, M.W., 1997. Patterns of DNA variability at X-linked loci in Mus domesticus. Genetics 147: 1303-1316.

Nachman, M.W., W.M. Brown, M. Stoneking, and C.F. Aquadro, 1996. Non-neutral mitochondrial DNA variation in humans and chimpanzees. Genetics 142: 953-963.

Nachman, M.W., and G.A. Churchill, 1996. Heterogeneity in rates of recombination across the mouse genome. Genetics 142: 537-548.

Nachman, M.W., 1996. the legacy of Motoo Kimura. (Invited Book Review). BioScience 46: 221-222.

Nachman, M.W., and J.B. Searle, 1995. Why is the house mouse karyotype so variable? Trends in Ecology & Evolution 10: 397-402.

Nachman, M.W. and C.F. Aquadro, 1994. Polymorphism and divergence at the 5' flanking region of the sex determining locus, Sry, in mice. Molecular Biology and Evolution 11: 539-547.

Nachman, M.W., S.N. Boyer, and C.F. Aquadro, 1994. Non-neutral evolution of the NADH dehydrogenase subunit 3 gene in mice. Proceedings of the National Academy of Sciences 91: 6364-6368.

Nachman, M.W., S.N. Boyer, J.B. Searle, and C.F. Aquadro, 1994. Mitochondrial DNA variation and the evolution of Robertsonian chromosomal races of house mice, Mus domesticus. Genetics 136: 1105-1120.

Nachman, M.W., 1992. Meiotic studies of Robertsonian polymorphisms in the South American marsh rate, Holochilus brasiliensis. Cytogenet. Cell Genet. 61: 17-24.

Nachman, M.W., 1992. Geographic patterns of chromosomal variation in South American marsh rats, Holochilus brasiliensis and H. vulpinus. Cytogenet. Cell Genet. 61: 10-16.

Klompen, J.S.H. and M.W. Nachman, 1990. Occurrence and control of the mange mite Notoedres muris in South American marsh rats. J. Wild. Dis. 26: 135-136.

Nachman, M.W., and P. Myers, 1989. Exceptional chromosomal mutations in a rodent population are not strongly underdominant. Proceedings of the National Academy of Sciences 86: 6666-6670.