Integrative Biology / Museum of Vertebrate Zoology
Broadly, I am interested in the genetic and mechanistic basis of environmental adaptation. For my PhD, I am investigating both the physiological ecology and the genetic basis of adaptation of the house mouse (Mus musculus) to different environments. Specifically, I will be using genomic and physiological approaches to investigate potential differences in metabolic traits between populations of house mice found in North and South America.
For my Master’s, I investigated the genetic and mechanistic underpinnings associated with the metabolic characteristics of hibernation. Specifically, I used RNAseq, proteomics, and mitochondrial assays to dissect the metabolic dynamics of both the brain and brown adipose tissue in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus.
Schwartz, C., Ballinger, M.A.
and Andrews, M.T. (in revision). Melatonin Receptor Signaling Contributes to
Neuroprotection upon Arousal from Torpor in the Thirteen-Lined Ground Squirrel. American Journal of
Physiology – Regulatory, Comparative and Integrative Physiology.
, Schwartz, C. and Andrews, M.T. (in prep). Enhanced Oxidative Capacity of Ground Squirrel
Brain Mitochondria During Hibernation.
, Hess, C., Napolitano, M.W., Bjork, J.A. and Andrews, M.T. (in prep). Interrogation of Brown
Adipose Tissue Mitochondria in a Mammalian Hibernator: from Gene Expression to Function.
, Callegari, E., Mackessy, S. and Smith, B. (in prep). Snake Venomics of the Prairie Rattlesnake,
Crotalus viridis: A Case of Intraspecific Variation in the Black Hills.