Jeffrey L. Boore

Adjunct Professor

Email: jlboore@berkeley.edu
Phone: (510) 724-3372
Lab Webpage: http://www.GenomeProjectSolutions.com

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Research Description

My research centers on bringing high-throughput genomic techniques to questions of evolutionary biology.

We are working on many diverse research projects, including:

  • Reconstruction of the evolutionary history of all gene families in sequenced genomes (see http://oomycetes.genomeprojectsolutions-databases.com/);
  • Comparisons of mitochondrial and chloroplast genomes (e.g., using gene rearrangements as a character for reconstructing evolutionary relationships) and Hox gene clusters (e.g., identifying the phylogenetic footprint of gene regulatory signals);
  • Leading whole eukaryotic genome sequencing projects

Some projects require significant molecular biology work, whereas others are primarily analytical. All of our research is computational, although we routinely contract for wet lab services such as whole genome sequencing.

Selected Publications

Rensing, S. A., D. Lang, (50 other authors) and J. L. Boore, 2008 The genome of the moss Physcomitrella patens reveals evolutionary insights into the conquest of land by plants.  Science 319: 64-69.
 
Jansen, R. K., Z. Cai, (13 other authors) and J. L. Boore, 2007  Analysis of 81 genes from 64 chloroplast genomes resolves relationships in angiosperms and identifies genome-scale evolutionary patterns. Proc. Natl. Acad. Sci. USA 104: 19369-19374.
 
Hoegg, S., J. V. Kuehl, J. L. Boore, and A. Meyer, 2007  Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni.  BMC Genomics 8: 317.
 
Tyler, B. M., S. Tripathi, X. Zhang, (49 other authors) and J. L. Boore, 2006 Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis.  Science 313: 1261-1266.
 
Boore, J. L., 2006  The use of genome-level characters for phylogenetic reconstruction. Trends Ecol. Evol. 21(8): 439-446.
 
Medina, M., A. G. Collins, T. L. Takaoka, J. Kuehl and J. L. Boore, 2006  Naked stony corals: Skeleton loss in Scleractinia.  Proc. Natl. Acad. Sci. USA 103: 9096-9100.
 
Dehal, P., and J. L. Boore, 2006 A phylogenomic gene cluster resource: The Phylogenetically Inferred Groups (PhIGs) database.  BMC Bioinformatics 7: 201.
 
Dehal, P., and J. L. Boore, 2005  Two rounds of genome duplication in the ancestral vertebrate genome.  PLoS Biology 3(10): e314.